Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847657 | 0.78 | NPSR1 (0.54) | HDAC6HDAC8HDAC11HDAC3NPSR1 | |
| SCHEMBL20847649 | 0.77 | HDAC6 (0.46) | HDAC6HDAC8HDAC11HDAC3SLC6A2 | |
| SCHEMBL20847595 | 0.76 | HDAC6 (0.48) | HDAC6HDAC8HDAC11HDAC3SLC40A1 | |
| SCHEMBL20847585 | 0.75 | HDAC6 (0.47) | HDAC6HDAC8HDAC11HDAC3NPSR1 | |
| SCHEMBL20847643 | 0.73 | CXCR4 (0.37) | SLC6A2SLC6A4SLC6A3CXCR4SSTR4 | |
| SCHEMBL20847564 | 0.73 | HDAC6 (0.62) | HDAC6HDAC8HDAC11HDAC3 | |
| SCHEMBL20847484 | 0.72 | HDAC6 (0.64) | HDAC6HDAC8HDAC11HDAC3 | |
| SCHEMBL20839235 | 0.72 | HDAC6 (0.67) | HDAC6HDAC8HDAC11HDAC3 | |
| SCHEMBL20847570 | 0.72 | HDAC6 (0.46) | HDAC6HDAC8HDAC11HDAC3 | |
| SCHEMBL20847759 | 0.70 | HDAC6 (0.52) | HDAC6HDAC8HDAC11HDAC3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2020-09-03 | — | — | US | disclosed |
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | MKI67, PKD1, ETV6 | HDAC6 499/4885HDAC8 1916/4885HDAC11 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.