Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847704 | 0.76 | RAB9A (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20847646 | 0.75 | GAA (0.36) | SLC6A2SLC6A4 | |
| SCHEMBL20847648 | 0.73 | HDAC6 (0.46) | CXCR4SSTR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20847591 | 0.72 | KCNH2 (0.40) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL20847650 | 0.72 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20847477 | 0.70 | SLC6A2 (0.39) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL20847568 | 0.70 | HTR2A (0.34) | — | |
| SCHEMBL20847761 | 0.69 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL26271669 | 0.69 | CXCR4 (0.48) | CXCR4SSTR4EPHX2SLC6A2SLC6A4 | |
| SCHEMBL20847629 | 0.69 | HTR2A (0.34) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |