Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873159 | 0.79 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL19878153 | 0.76 | ALK (0.50) | FERMT2MEN1KMT2ALMNAMAPT | |
| SCHEMBL4355081 | 0.76 | NR4A2 (0.61) | CCR1FERMT2MEN1KMT2AMAPT | |
| SCHEMBL13632508 | 0.76 | GAK (0.42) | HTR1AADRA1DADRA1AADRA1BPARP1 | |
| SCHEMBL317506 | 0.76 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL20427414 | 0.76 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL2658022 | 0.76 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL31452673 | 0.76 | NR4A2 (0.61) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL3071029 | 0.76 | NR4A2 (0.61) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL5543680 | 0.76 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |