Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 19/20 | 0.66 |
| ▸ | RARB | P10826 | 19/20 | 0.66 |
| ▸ | RARG | P13631 | 18/20 | 0.66 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20636874 | 0.82 | RARB (0.66) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL20636833 | 0.82 | RARB (0.65) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6210444 | 0.80 | RARA (1.00) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6261635 | 0.78 | RARB (0.57) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8771774 | 0.77 | RARB (0.60) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL19342912 | 0.76 | RARA (0.73) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8771694 | 0.74 | RARB (0.56) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL19342910 | 0.74 | RARB (0.66) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6240831 | 0.74 | RARA (0.76) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6232868 | 0.73 | RARB (1.00) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216407-A1 | RETINOID COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2020-07-09 | — | — | US | disclosed |
| US-10556879-B2 | Retinoid compound, preparation method therefor, intermediates thereof and application thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADMENY OF SCIENCES (CN) | 2020-02-11 | — | — | US | disclosed |
| US-20190092744-A1 | RETINOID COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092744-A1 | RETINOID COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF AND APPLICATION THEREOF | RARA, RARB, RARG | RARA 1/4885RARB 2/4885RARG 3/4885 |
| US-10556879-B2 | Retinoid compound, preparation method therefor, intermediates thereof and application thereof | RARA, RARB, RARG | RARA 1/4885RARB 2/4885RARG 3/4885 |
| US-20200216407-A1 | RETINOID COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF AND APPLICATION THEREOF | RARA, RARB, RARG | RARA 1/4885RARB 2/4885RARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.