Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.67 |
| ▸ | APP | P05067 | 2/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22874653 | 0.88 | MAOB (0.67) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL16440939 | 0.85 | MAOB (0.67) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL21340442 | 0.84 | MAOB (0.69) | MAOBAPPNR4A2NPC1RAB9A | |
| SCHEMBL19604518 | 0.84 | MAOB (0.67) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL11959895 | 0.84 | MAOB (0.67) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL18937890 | 0.83 | MAOB (0.71) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL16440940 | 0.82 | MAOB (0.63) | MAOBAPPNR4A2CA12CA1 | |
| SCHEMBL13977985 | 0.82 | APP (0.69) | MAOBAPPRXRARXRBNPC1 | |
| SCHEMBL8272576 | 0.82 | RXRA (0.66) | APPRXRARXRBLMNANPC1 | |
| SCHEMBL15336496 | 0.82 | MAOB (0.61) | MAOBAPPRXRARXRBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486002-B1 | SUBSTITUTED HETEROARYL- AND ARYL- CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE | ORYZON GENOMICS SA (ES) | 2019-03-27 | — | — | EP | disclosed |