SCHEMBL20848558

SCHEMBL20848558

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc(-c2c(C(F)(F)F)cccc2C(F)(F)F)cc1-c1ccc(C#N)cc1-n1c2ccc(C)cc2c2cc(C)ccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.33
KIF11 P52732 1/20 0.33
ELANE P08246 2/20 0.32
SCN9A Q15858 1/20 0.31
NSD2 O96028 1/20 0.31
HSD11B1 P28845 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
ATM Q13315 1/20 0.31
MAT2A P31153 1/20 0.30
CYP11B2 P19099 1/20 0.30
ACP1 P24666 1/20 0.30
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848563 0.96 AR (0.35) ARPTGDR2KIF11ELANEHSD11B1
SCHEMBL20849195 0.96 AR (0.37) ARPTGDR2KIF11ELANESCN9A
SCHEMBL20848890 0.96 AR (0.39) ARPTGDR2KIF11ELANESCN9A
SCHEMBL20849637 0.95 AR (0.39) ARPTGDR2KIF11ELANESCN9A
SCHEMBL20849449 0.94 AR (0.40) ARKIF11ELANESCN9ANSD2
SCHEMBL20849447 0.93 AR (0.45) ARKIF11SCN9AALDH1A1HPGD
SCHEMBL20849041 0.93 KIF11 (0.36) ARKIF11NSD2MAT2AACP1
SCHEMBL20849193 0.92 AR (0.35) ARPTGDR2KIF11ELANEHSD11B1
SCHEMBL20848888 0.92 AR (0.36) ARPTGDR2KIF11ELANEHSD11B1
SCHEMBL20849465 0.91 AR (0.33) ARKIF11ELANESCN9AMAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978646-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-13 US disclosed
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10978646-B2 Organic molecules for use in optoelectronic devices OCIAD2, OCIAD1, POU2F1 AR 3706/4885PTGDR2 3905/4885KIF11 419/4885
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 AR 3706/4885PTGDR2 3905/4885KIF11 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.