SCHEMBL20848784

SCHEMBL20848784

Cc1nc(C)nc(-c2ccc3c(c2)c2cc(-c4nc(C)nc(C)n4)ccc2n3-c2ccc(C#N)cc2-c2cc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)ccc2-n2c3ccc(-c4nc(C)nc(C)n4)cc3c3cc(-c4nc(C)nc(C)n4)ccc32)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.34
FEN1 P39748 2/20 0.34
CYP2C9 P11712 1/20 0.34
SCN9A Q15858 1/20 0.34
ELANE P08246 6/20 0.33
DGAT1 O75907 1/20 0.33
SOAT1 P35610 1/20 0.33
KCNH2 Q12809 1/20 0.33
KIF11 P52732 1/20 0.33
NSD2 O96028 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
CNR1 P21554 2/20 0.31
MAT2A P31153 1/20 0.31
PTGER4 P35408 1/20 0.30
XDH P47989 1/20 0.30
SLC22A12 Q96S37 1/20 0.30
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848711 0.96 CYP2C9 (0.33) ALOX5APFEN1CYP2C9SCN9AELANE
SCHEMBL20848976 0.96 CYP2C9 (0.33) ALOX5APFEN1CYP2C9SCN9AELANE
SCHEMBL20848787 0.96 PTGER4 (0.37) ALOX5APFEN1CYP2C9SCN9AELANE
SCHEMBL20848708 0.93 ALOX5AP (0.34) ALOX5APFEN1CYP2C9SCN9AELANE
SCHEMBL20848975 0.93 PTGER4 (0.36) ALOX5APFEN1CYP2C9SCN9AELANE
SCHEMBL22985120 0.91 ALOX5AP (0.39) ALOX5APFEN1SCN9AELANEDGAT1
SCHEMBL22985356 0.91 NSD2 (0.33) KIF11NSD2PTGER4PSEN1PSEN2
SCHEMBL22985243 0.91 NSD2 (0.33) KIF11NSD2PTGER4XDHSLC22A12
SCHEMBL21399442 0.91 KIF11 (0.35) ELANEDGAT1SOAT1KCNH2KIF11
SCHEMBL22985707 0.90 PTGER4 (0.39) CYP2C9ELANENSD2PTGER4PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978646-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-13 US disclosed
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10978646-B2 Organic molecules for use in optoelectronic devices OCIAD2, OCIAD1, POU2F1 ALOX5AP 3630/4885FEN1 3586/4885CYP2C9 725/4885
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 ALOX5AP 3630/4885FEN1 3586/4885CYP2C9 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.