SCHEMBL20848930

SCHEMBL20848930

Cc1cccc(-c2ccc3c(c2)c2cc(-c4cccc(C)c4)ccc2n3-c2cccc(C#N)c2-c2c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cccc2-n2c3ccc(-c4cccc(C)c4)cc3c3cc(-c4cccc(C)c4)ccc32)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.45
ENPP1 P22413 1/20 0.35
ICMT O60725 1/20 0.35
MAT2A P31153 1/20 0.34
SIRT2 Q8IXJ6 2/20 0.33
SIRT1 Q96EB6 1/20 0.33
SSTR2 P30874 1/20 0.33
XDH P47989 1/20 0.32
GABRA1 P14867 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRB2 P47870 1/20 0.32
GABRA4 P48169 1/20 0.32
GABRE P78334 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20849254 0.96 AR (0.42) ARENPP1ICMTMAT2ASIRT2
SCHEMBL20848571 0.94 AR (0.38) ARICMTSSTR2XDHGABRA1
SCHEMBL20848936 0.94 AR (0.38) ARICMTMAT2ASSTR2XDH
SCHEMBL20848933 0.93 AR (0.40) ARENPP1ICMTSSTR2XDH
SCHEMBL20848581 0.91 AR (0.34) ARICMTSSTR2GABRA1GABRG2
SCHEMBL20849092 0.91 AR (0.35) ARICMTSSTR2PGR
SCHEMBL20848573 0.90 AR (0.38) ARSSTR2XDHGABRA1GABRG2
SCHEMBL20848932 0.90 AR (0.38) ARENPP1ICMTSSTR2PGR
SCHEMBL20848535 0.90 AR (0.44) ARENPP1ICMTMAT2ASIRT2
SCHEMBL20849332 0.89 MAT2A (0.38) ARENPP1MAT2ASSTR2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978646-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-13 US disclosed
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10978646-B2 Organic molecules for use in optoelectronic devices OCIAD2, OCIAD1, POU2F1 AR 3706/4885ENPP1 4565/4885ICMT 616/4885
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 AR 3706/4885ENPP1 4565/4885ICMT 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.