Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987452 | 0.92 | KDM4C (0.51) | KMT2AMEN1KDM4CL3MBTL1TAAR1 | |
| SCHEMBL6042775 | 0.86 | KMT2A (0.45) | KMT2AMEN1KDM4CL3MBTL1NPC1 | |
| SCHEMBL6042771 | 0.86 | KMT2A (0.45) | KMT2AMEN1KDM4CL3MBTL1NPC1 | |
| SCHEMBL10998191 | 0.80 | TAAR1 (0.44) | KMT2AMEN1L3MBTL1TAAR1NPC1 | |
| SCHEMBL30416895 | 0.78 | MEN1 (0.53) | KMT2AMEN1KDM4CL3MBTL1NPC1 | |
| SCHEMBL10341111 | 0.78 | HRH3 (0.37) | KMT2AMEN1KDM4CTAAR1NPC1 | |
| SCHEMBL9673310 | 0.77 | KDM4C (0.53) | KMT2AMEN1KDM4CL3MBTL1NPC1 | |
| SCHEMBL80944 | 0.76 | KDM4C (0.54) | KMT2AMEN1KDM4CL3MBTL1NPC1 | |
| SCHEMBL11024894 | 0.76 | MEN1 (0.54) | KMT2AMEN1KDM4CL3MBTL1NPC1 | |
| SCHEMBL1008487 | 0.75 | MEN1 (0.54) | KMT2AMEN1KDM4CL3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854791-B1 | NOVEL THIOPHENE COMPOUND AND PROCESS FOR PRODUCING CAFFENOFURAN OR ANALOGUE THEREOF FROM THE SAME | SAN EI GEN FFI INC (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-7897790-B2 | synthetic intermediate that is useful for efficient production of kahweofuran; flavoring; when thiophene compound is reacted in hydrogen atmosphere using transition metal catalyst, cyclization occurs simultaneously with reduction, to produce a 2,3-dihydrothieno[2,3c]furan skeleton in a single step | SAN-EI GEN F.F.I., INC. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | SAN EI GEN F.F.I., INC. (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1854791-A1 | NOVEL THIOPHENE COMPOUND AND PROCESS FOR PRODUCING CAFFENOFURAN OR ANALOGUE THEREOF FROM THE SAME | SAN-EI GEN F.F.I., INC. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | CYP4F3, CBR3, GTF3C4 | KMT2A 1406/4885MEN1 2693/4885KDM4C 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.