SCHEMBL20848995

SCHEMBL20848995

Cc1ccc2c(c1)c1ccccc1n2-c1ccc(C#N)cc1-c1cc(-c2c(C(F)(F)F)cccc2C(F)(F)F)ccc1-n1c2ccccc2c2cc(C)ccc21

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.37
PTGER4 P35408 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
ACP1 P24666 1/20 0.33
RORC P51449 2/20 0.33
HSD11B1 P28845 1/20 0.32
KIF11 P52732 1/20 0.32
PDE9A O76083 1/20 0.32
PDE1C Q14123 1/20 0.32
SLC22A12 Q96S37 1/20 0.31
ELANE P08246 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20849637 0.96 AR (0.39) ARPTGDR2ACP1HSD11B1KIF11
SCHEMBL20848563 0.95 AR (0.35) ARPTGER4PTGDR2ACP1RORC
SCHEMBL20849193 0.95 AR (0.35) ARPTGER4PTGDR2ACP1RORC
SCHEMBL20849466 0.94 AR (0.40) ARPTGER4ACP1RORCKIF11
SCHEMBL20849642 0.93 AR (0.44) ARPTGER4ACP1RORCKIF11
SCHEMBL20848561 0.93 AR (0.36) ARPTGER4ACP1RORCKIF11
SCHEMBL20849615 0.93 AR (0.37) ARPTGER4PTGDR2ACP1RORC
SCHEMBL21399277 0.92 PTGDR2 (0.34) ARPTGER4PTGDR2ACP1RORC
SCHEMBL20849195 0.91 AR (0.37) ARPTGDR2ACP1HSD11B1KIF11
SCHEMBL20848558 0.91 AR (0.37) ARPTGDR2ACP1HSD11B1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978646-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-13 US disclosed
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10978646-B2 Organic molecules for use in optoelectronic devices OCIAD2, OCIAD1, POU2F1 AR 3706/4885PTGER4 3716/4885PTGDR2 3905/4885
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 AR 3706/4885PTGER4 3716/4885PTGDR2 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.