Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.33 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20850745 | 0.95 | CYP1A2 (0.37) | GAATP53GRM2PLA2G6PLA2G4A | |
| SCHEMBL23841969 | 0.93 | CYP1A2 (0.39) | GRM2CYP1A2 | |
| SCHEMBL20470608 | 0.89 | GRM2 (0.38) | GAATP53GRM2NPC1RAB9A | |
| SCHEMBL23845211 | 0.84 | GRM2 (0.39) | GRM2CYP1A2 | |
| SCHEMBL20850698 | 0.80 | TP53 (0.36) | GAATP53GRM2CYP1A2ABCB1 | |
| SCHEMBL24846890 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL20850730 | 0.74 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL20643385 | 0.66 | POLB (0.37) | GRM2CYP1A2 | |
| SCHEMBL23744393 | 0.64 | GAA (0.35) | GAATP53ABL1RIN1TDP1 | |
| SCHEMBL818514 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019060742-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC (US) | 2019-03-28 | — | — | WO | disclosed |