Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 15/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20470608 | 0.95 | GRM2 (0.38) | GRM2 | |
| SCHEMBL20850745 | 0.90 | CYP1A2 (0.37) | GRM2CYP1A2POLBFASN | |
| SCHEMBL23841969 | 0.88 | CYP1A2 (0.39) | GRM2CYP1A2POLBFASN | |
| SCHEMBL20850679 | 0.84 | GAA (0.35) | GRM2CYP1A2 | |
| Benzene SCHEMBL27463071 | 0.76 | GRM2 (0.43) | GRM2POLBFASN | |
| SCHEMBL20850698 | 0.75 | TP53 (0.36) | GRM2CYP1A2 | |
| SCHEMBL20643385 | 0.71 | POLB (0.37) | GRM2CYP1A2POLBFASN | |
| SCHEMBL20850730 | 0.69 | CYP1A2 (0.30) | CYP1A2 | |
| SCHEMBL24848256 | 0.66 | TP53 (0.34) | — | |
| SCHEMBL5694481 | 0.65 | CYP1A2 (0.46) | CYP1A2POLBFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |