Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.58 |
| ▸ | PGR | P06401 | 6/20 | 0.58 |
| ▸ | SHBG | P04278 | 4/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907662 | 1.00 | AR (0.58) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL15515496 | 1.00 | AR (0.58) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL14946867 | 1.00 | AR (0.58) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL23397835 | 0.89 | SHBG (0.51) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL20851695 | 0.89 | SHBG (0.51) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL22648669 | 0.83 | SHBG (0.64) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL20851703 | 0.81 | ESR1 (0.57) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL28719362 | 0.81 | ESR1 (0.57) | ARPGRSHBGESR1OPRM1 | |
| SCHEMBL12446091 | 0.80 | SHBG (0.69) | ARPGRSHBGESR1SERPINA6 | |
| SCHEMBL4437111 | 0.80 | SHBG (0.69) | ARPGRSHBGESR1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034716-B2 | Process and new intermediates for the preparation of 11-methylene steroids | CRYSTAL PHARMA, S.A.U. (ES) | 2021-06-15 | — | — | US | disclosed |
| US-20190092807-A1 | PROCESS AND NEW INTERMEDIATES FOR THE PREPARATION OF 11-METHYLENE STEROIDS | CURIA SPAIN, S.A.U. (ES) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034716-B2 | Process and new intermediates for the preparation of 11-methylene steroids | CYP17A1, HSD17B11, CYP19A1 | AR 70/4885PGR 38/4885SHBG 25/4885 |
| US-20190092807-A1 | PROCESS AND NEW INTERMEDIATES FOR THE PREPARATION OF 11-METHYLENE STEROIDS | CYP19A1, CYP17A1, HSD17B11 | AR 90/4885PGR 29/4885SHBG 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.