Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 16/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083092 | 0.88 | CXCR4 (0.42) | USP30CXCR4GABRA1GABRG2GABRB3 | |
| SCHEMBL2082027 | 0.84 | CXCR4 (0.40) | USP30CXCR4UCHL1 | |
| SCHEMBL12935396 | 0.84 | CXCR4 (0.40) | CXCR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2082385 | 0.84 | CXCR4 (0.42) | CXCR4 | |
| SCHEMBL2085538 | 0.83 | CXCR4 (0.38) | CXCR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2085542 | 0.82 | CXCR4 (0.39) | CXCR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12935380 | 0.82 | CXCR4 (0.37) | CXCR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12935391 | 0.81 | CXCR4 (0.38) | CXCR4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2086381 | 0.81 | CXCR4 (0.40) | USP30CXCR4UCHL1 | |
| SCHEMBL2086372 | 0.80 | MEN1 (0.45) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613613-B1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| US-7863293-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED CORPORATION (CA) | 2008-10-16 | — | — | US | disclosed |
| US-7291631-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2007-11-06 | — | — | US | disclosed |
| US-20040209921-A1 | CXCR4 chemokine receptor binding comounds | ANORMED CORPORATION (CA) | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209921-A1 | CXCR4 chemokine receptor binding comounds | CXCR4, CXCR1, CXCR3 | USP30 4208/4885CXCR4 1/4885GABRA1 2491/4885 |
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | CXCR4, CXCR1, CXCR3 | USP30 4224/4885CXCR4 1/4885GABRA1 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.