Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.66 |
| ▸ | DRD4 | P21917 | 10/20 | 0.66 |
| ▸ | DRD3 | P35462 | 10/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23067930 | 0.83 | DRD2 (0.92) | DRD2DRD4DRD3NPC1KDM4E | |
| SCHEMBL2470398 | 0.81 | DRD2 (0.68) | DRD2DRD4DRD3NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL8053903 | 0.81 | DRD2 (0.88) | DRD2DRD4DRD3NPC1KDM4E | |
| SCHEMBL313373 | 0.79 | DRD2 (0.64) | DRD2DRD4DRD3NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL8042240 | 0.79 | DRD2 (0.92) | DRD2DRD4DRD3NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL21595673 | 0.79 | DRD2 (0.66) | DRD2DRD4DRD3NPC1KDM4E | |
| SCHEMBL11453076 | 0.79 | DRD2 (0.66) | DRD2DRD4DRD3NPC1KDM4E | |
| SCHEMBL14174988 | 0.79 | DRD2 (0.71) | DRD2DRD4DRD3NPC1KDM4E | |
| SCHEMBL10509067 | 0.78 | DRD2 (0.75) | DRD2DRD4DRD3NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL11127451 | 0.78 | DRD2 (0.63) | DRD2DRD4DRD3NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753605-B1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-03-27 | — | — | EP | disclosed |