Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | RORA | P35398 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | RORB | Q92753 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628011 | 0.78 | MEN1 (0.64) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4220374 | 0.78 | MEN1 (0.64) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL19526836 | 0.75 | HTR7 (0.57) | PGRRORARORCRORBPSEN1 | |
| SCHEMBL6326696 | 0.73 | MEN1 (0.58) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL30151601 | 0.73 | MEN1 (0.58) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4212491 | 0.72 | MEN1 (0.56) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL10413247 | 0.72 | MEN1 (0.56) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11607923 | 0.72 | MEN1 (0.56) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9275476 | 0.72 | MEN1 (0.56) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11605849 | 0.72 | MEN1 (0.56) | KDM4EMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019058393-A1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-03-28 | — | — | WO | disclosed |