Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17558296 | 0.92 | DGAT2 (1.00) | DGAT2 | |
| SCHEMBL17571886 | 0.90 | DGAT2 (0.82) | DGAT2 | |
| SCHEMBL19397241 | 0.89 | DGAT2 (0.83) | DGAT2 | |
| SCHEMBL17558256 | 0.89 | DGAT2 (1.00) | DGAT2 | |
| SCHEMBL20853695 | 0.85 | DGAT2 (0.82) | DGAT2 | |
| SCHEMBL20853696 | 0.81 | DGAT2 (0.68) | DGAT2 | |
| SCHEMBL20861432 | 0.80 | DGAT2 (0.83) | DGAT2 | |
| SCHEMBL17558236 | 0.79 | DGAT2 (1.00) | DGAT2 | |
| SCHEMBL20861597 | 0.79 | DGAT2 (0.82) | DGAT2 | |
| SCHEMBL17558251 | 0.79 | DGAT2 (1.00) | DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188731-B1 | ISOQUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | MERCK SHARP & DOHME (US) | 2019-04-03 | — | — | EP | claimed |