Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 20/20 | 0.64 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445163 | 1.00 | QPCT (0.64) | QPCTQPCTL | |
| SCHEMBL20853782 | 1.00 | QPCT (0.64) | QPCTQPCTL | |
| SCHEMBL20853751 | 1.00 | QPCT (0.64) | QPCTQPCTL | |
| SCHEMBL20853792 | 0.90 | QPCT (0.52) | QPCTQPCTL | |
| SCHEMBL29445215 | 0.90 | QPCT (0.52) | QPCTQPCTL | |
| SCHEMBL29445191 | 0.90 | QPCT (0.52) | QPCTQPCTL | |
| SCHEMBL1444389 | 0.82 | QPCT (0.84) | QPCT | |
| SCHEMBL1445013 | 0.82 | QPCT (0.84) | QPCT | |
| SCHEMBL1444387 | 0.82 | QPCT (0.84) | QPCT | |
| SCHEMBL1444549 | 0.78 | QPCT (0.50) | QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279690-B2 | Inhibitors of glutaminyl cyclase | VIVORIAN THERAPEUTICS N.V | 2022-03-22 | — | — | US | claimed |
| CN-111315738-B | Inhibitors of glutaminyl cyclase | 维沃永治疗股份公司 | 2021-08-03 | — | — | CN | claimed |
| US-20200223825-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | VIVORYON THERAPEUTICS N.V (DE) | 2020-07-16 | — | — | US | claimed |
| CN-111315738-A | Inhibitors of glutaminyl cyclase | 维沃永治疗股份公司 | 2020-06-19 | — | — | CN | claimed |
| EP-3461819-B1 | INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2020-05-27 | — | — | EP | claimed |
| US-11279690-B2 | Inhibitors of glutaminyl cyclase | VIVORIAN THERAPEUTICS N.V | 2022-03-22 | — | — | US | disclosed |
| CN-111315738-B | Inhibitors of glutaminyl cyclase | 维沃永治疗股份公司 | 2021-08-03 | — | — | CN | disclosed |
| US-20200223825-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | VIVORYON THERAPEUTICS N.V (DE) | 2020-07-16 | — | — | US | disclosed |
| CN-111315738-A | Inhibitors of glutaminyl cyclase | 维沃永治疗股份公司 | 2020-06-19 | — | — | CN | disclosed |
| EP-3461819-B1 | INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2020-05-27 | — | — | EP | disclosed |
| EP-3461819-B1 | INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019063414-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2019-04-04 | — | — | WO | disclosed |
| EP-3461819-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | Probiodrug AG (DE) | 2019-04-03 | — | — | EP | disclosed |
| EP-3461819-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | Probiodrug AG (DE) | 2019-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223825-A1 | INHIBITORS OF GLUTAMINYL CYCLASE | QPCT, QPCTL, GLUL | QPCT 1/4885QPCTL 2/4885 |
| US-11279690-B2 | Inhibitors of glutaminyl cyclase | QPCT, QPCTL, GLUL | QPCT 1/4885QPCTL 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.