SCHEMBL20855010

SCHEMBL20855010

Cn1c2ccc(S(=O)(=O)O)cc2c(=O)c2cc(S(=O)(=O)O)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 2/20 0.47
PARG Q86W56 3/20 0.41
LMNA P02545 4/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HPGD P15428 1/20 0.41
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CASP6 P55212 1/20 0.41
KDM4E B2RXH2 2/20 0.40
APEX1 P27695 1/20 0.40
MITF O75030 1/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25520016 0.92 PIK3CG (0.42) PIK3CGPARGLMNAALDH1A1MEN1
SCHEMBL22282380 0.87 MAPT (0.56) LMNAALDH1A1MEN1KMT2AHPGD
SCHEMBL13681190 0.85 PIK3CG (0.42) PIK3CGPARGLMNAALDH1A1MEN1
SCHEMBL54882 0.82 PIK3CG (0.47) PIK3CGPARGLMNAMEN1KMT2A
SCHEMBL29558921 0.82 PIK3CG (0.47) PIK3CGPARGLMNAMEN1KMT2A
SCHEMBL6390356 0.81 PIK3CG (0.72) PIK3CGPARGLMNAALDH1A1SMN1; SMN2
SCHEMBL8351226 0.80 PARG (0.47) PIK3CGPARGLMNAALDH1A1HPGD
Hydrochloric Acid SCHEMBL28174265 0.80 PIK3CG (0.70) PIK3CGPARGLMNAALDH1A1SMN1; SMN2
SCHEMBL6392996 0.79 PARG (0.61) PIK3CGPARGLMNAALDH1A1MEN1
Hydrochloric Acid SCHEMBL28174270 0.78 PARG (0.60) PIK3CGPARGLMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION REVVITY HEALTH SCIENCES, INC. 2023-05-25 US disclosed
US-11549017-B2 NIR to SWIR fluorescent compounds for imaging and detection PERKINELMER HEALTH SCIENCES, INC. (US) 2023-01-10 US disclosed
US-20190100654-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION REVVITY HEALTH SCIENCES, INC. 2019-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11549017-B2 NIR to SWIR fluorescent compounds for imaging and detection SMARCD1, SMARCE1, SMARCB1 PIK3CG 2889/4885PARG 1087/4885LMNA 717/4885
US-20190100654-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION SMARCD1, SMARCE1, SMARCB1 PIK3CG 2889/4885PARG 1087/4885LMNA 717/4885
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION SMARCD1, SMARCE1, SMARCB1 PIK3CG 2889/4885PARG 1087/4885LMNA 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.