Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | PARG | Q86W56 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558921 | 1.00 | PIK3CG (0.47) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL3761642 | 0.92 | ATM (0.51) | PIK3CGHTTNPC1RAB9AMEN1 | |
| SCHEMBL17715367 | 0.87 | PIK3CG (0.39) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL27651563 | 0.83 | MAPT (0.54) | PIK3CGHTTMEN1KMT2AATM | |
| SCHEMBL20855010 | 0.82 | PIK3CG (0.47) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL17832062 | 0.81 | PIK3CG (0.72) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL26090948 | 0.80 | PARG (0.64) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL17825124 | 0.79 | PARG (0.61) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL5865904 | 0.77 | PARG (0.47) | PIK3CGPARGTP53 | |
| SCHEMBL1278983 | 0.76 | KDM4E (0.58) | PKMHTTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159762-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | REVVITY HEALTH SCIENCES, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230159762-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | REVVITY HEALTH SCIENCES, INC. | 2023-05-25 | — | — | US | disclosed |
| US-11549017-B2 | NIR to SWIR fluorescent compounds for imaging and detection | PERKINELMER HEALTH SCIENCES, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| CN-108314663-B | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | 多格伍德药品公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2019067180-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | PERKINELMER HEALTH SCIENCES, INC. (US) | 2019-04-04 | — | — | WO | disclosed |
| US-20190100654-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | REVVITY HEALTH SCIENCES, INC. | 2019-04-04 | — | — | US | disclosed |
| US-9446021-B2 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | DOGWOOD PHARMACEUTICALS, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-9446021-B2 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | DOGWOOD PHARMACEUTICALS, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-9446021-B2 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | DOGWOOD PHARMACEUTICALS, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| EP-2152258-B1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2016-05-04 | — | — | EP | disclosed |
| US-8129519-B2 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | ALLERGAN SALES, LLC | 2012-03-06 | — | — | US | disclosed |
| US-8129519-B2 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | ALLERGAN SALES, LLC | 2012-03-06 | — | — | US | disclosed |
| WO-2010082912-A1 | DERIVATIVES OF MULTI-RING AROMATIC COMPOUNDS AND USES AS ANTI-TUMOR AGENTS | AVALON PHARMACEUTICALS (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010082912-A1 | DERIVATIVES OF MULTI-RING AROMATIC COMPOUNDS AND USES AS ANTI-TUMOR AGENTS | AVALON PHARMACEUTICALS (US) | 2010-07-22 | — | — | WO | disclosed |
| US-20100137354-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | ALLERGAN SALES, LLC | 2010-06-03 | — | — | US | disclosed |
| US-20100137354-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | ALLERGAN SALES, LLC | 2010-06-03 | — | — | US | disclosed |
| US-20100137354-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | ALLERGAN SALES, LLC | 2010-06-03 | — | — | US | disclosed |
| EP-2152258-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | Avalon Pharmaceuticals (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008140792-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008140792-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137354-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | WNT1, CTNND1, CTNNB1 | PIK3CG 3284/4885PARG 4086/4885PKM 4502/4885 |
| US-11549017-B2 | NIR to SWIR fluorescent compounds for imaging and detection | SMARCD1, SMARCE1, SMARCB1 | PIK3CG 2889/4885PARG 1087/4885PKM 2856/4885 |
| US-20190100654-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | SMARCD1, SMARCE1, SMARCB1 | PIK3CG 2889/4885PARG 1087/4885PKM 2856/4885 |
| US-20230159762-A1 | NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION | SMARCD1, SMARCE1, SMARCB1 | PIK3CG 2889/4885PARG 1087/4885PKM 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.