Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523615 | 0.86 | AR (0.49) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL20855762 | 0.83 | AR (0.46) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL20855761 | 0.83 | AR (0.46) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL16955918 | 0.83 | AR (0.46) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL20855659 | 0.83 | AR (0.46) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL20855662 | 0.83 | AR (0.46) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL17731549 | 0.81 | AR (0.47) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL17731548 | 0.81 | AR (0.47) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL18923587 | 0.80 | AR (0.44) | ARSLC6A4MEN1KMT2AMCL1 | |
| SCHEMBL171796 | 0.80 | AR (0.47) | ARSLC6A4MEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |