Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21023399 | 0.88 | AR (0.42) | ARSLC6A4TRPV4CTSAKDM1A | |
| SCHEMBL171796 | 0.87 | AR (0.47) | ARSLC6A4CTSAKDM1AICMT | |
| SCHEMBL22796911 | 0.87 | AR (0.44) | ARSLC6A4TRPV4 | |
| SCHEMBL523615 | 0.83 | AR (0.49) | ARSLC6A4KDM1AICMTMEN1 | |
| SCHEMBL20855644 | 0.83 | AR (0.43) | ARSLC6A4TRPV4KDM1AMEN1 | |
| SCHEMBL20855647 | 0.83 | AR (0.43) | ARSLC6A4TRPV4KDM1AMEN1 | |
| SCHEMBL24767631 | 0.81 | AR (0.40) | ARSLC6A4TRPV4CTSAKDM1A | |
| SCHEMBL20869018 | 0.80 | SLC6A4 (0.43) | ARSLC6A4TRPV4CTSAKDM1A | |
| SCHEMBL20855659 | 0.80 | AR (0.46) | ARSLC6A4CTSAKDM1AMEN1 | |
| SCHEMBL20855762 | 0.80 | AR (0.46) | ARSLC6A4KDM1AICMTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807968-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-20 | — | — | US | disclosed |
| US-20200048221-A1 | SUBSTITUTED 2-(HET)ARYLIMIDAZOLYLCARBOXYAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| US-10336748-B2 | Methyoxy-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | PFIZER INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-9670201-B2 | Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | PFIZER INC. (US) | 2017-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048221-A1 | SUBSTITUTED 2-(HET)ARYLIMIDAZOLYLCARBOXYAMIDES AS PESTICIDES | DDT, CYP4X1, CYP4Z1 | AR 3988/4885SLC6A4 3369/4885TRPV4 2051/4885 |
| US-10807968-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | AR 3988/4885SLC6A4 3369/4885TRPV4 2051/4885 |
| US-10336748-B2 | Methyoxy-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | RORC, RORB, RORA | AR 1975/4885SLC6A4 4461/4885TRPV4 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.