Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 9/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403726 | 0.77 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL993501 | 0.77 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL8472572 | 0.75 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL992169 | 0.74 | TSHR (0.36) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2119954 | 0.71 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2121838 | 0.71 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2123092 | 0.71 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2124380 | 0.71 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2122750 | 0.71 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2120815 | 0.71 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688042-B1 | BIS-PHENYL-PHENOXY POLYOLEFIN CATALYSTS HAVING TWO METHYLENETRIALKYLSILICON LIGANDS ON THE METAL FOR IMPROVED SOLUBILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-11-22 | — | — | EP | disclosed |
| US-11066489-B2 | Bis-phenyl-phenoxy polyolefin catalysts having two methylenetrialkylsilicon ligands on the metal for improved solubility | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200270376-A1 | BIS-PHENYL-PHENOXY POLYOLEFIN CATALYSTS HAVING TWO METHYLENETRIALKYLSILICON LIGANDS ON THE METAL FOR IMPROVED SOLUBILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-08-27 | — | — | US | disclosed |
| EP-3688042-A1 | BIS-PHENYL-PHENOXY POLYOLEFIN CATALYSTS HAVING TWO METHYLENETRIALKYLSILICON LIGANDS ON THE METAL FOR IMPROVED SOLUBILITY | Dow Global Technologies LLC (US) | 2020-08-05 | — | — | EP | disclosed |
| CN-111133010-A | Bis-phenyl-phenoxy polyolefin catalysts with two methylenetrialkylsilyl ligands on the metal for improved solubility | 陶氏环球技术有限责任公司 | 2020-05-08 | — | — | CN | disclosed |
| WO-2019067274-A1 | BIS-PHENYL-PHENOXY POLYOLEFIN CATALYSTS HAVING TWO METHYLENETRIALKYLSILICON LIGANDS ON THE METAL FOR IMPROVED SOLUBILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066489-B2 | Bis-phenyl-phenoxy polyolefin catalysts having two methylenetrialkylsilicon ligands on the metal for improved solubility | CBX3, CBX4, CBX6 | TSHR 4659/4885THRB 4487/4885GGPS1 2074/4885 |
| US-20200270376-A1 | BIS-PHENYL-PHENOXY POLYOLEFIN CATALYSTS HAVING TWO METHYLENETRIALKYLSILICON LIGANDS ON THE METAL FOR IMPROVED SOLUBILITY | CBX3, CBX4, CBX6 | TSHR 4659/4885THRB 4487/4885GGPS1 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.