Sugi Predict

Sugi Predict / Compounds / Tyrosine

Tyrosine

Tyrosine

SCHEMBL20857031

CC(C)CC(N)C(=O)O.CCC(C)C(N)C(=O)O.NC(CO)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O.NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 2/20 0.52
▸ ALPI P09923 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ PTGS1 P23219 1/20 0.48
▸ XIAP P98170 1/20 0.48
▸ ACE P12821 7/20 0.46
▸ ANPEP P15144 1/20 0.46
▸ RNPEP Q9H4A4 1/20 0.46
▸ DNPEP Q9ULA0 1/20 0.46
▸ SLC1A3 P43003 1/20 0.43
▸ SLC1A2 P43004 1/20 0.43
▸ SLC1A1 P43005 1/20 0.43
▸ LTA4H P09960 1/20 0.43
▸ OPRD1 P41143 2/20 0.41
▸ OPRM1 P35372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL3131428 0.92 SLC7A5 (0.53) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL3131438 0.92 SLC7A5 (0.53) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL7795418 0.92 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL27347200 0.92 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL18249988 0.92 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL25212292 0.91 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28774219 0.90 SLC7A5 (0.49) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28434257 0.90 SLC7A5 (0.49) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28098006 0.90 SLC7A5 (0.49) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL16914544 0.90 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3688021-A1 USE OF METFORMIN AND ANALOGS THEREOF TO REDUCE RAN PROTEIN LEVELS IN THE TREATMENT OF NEUROLOGICAL DISORDERS University of Florida Research Foundation, Incorporated (US) 2020-08-05 — — EP disclosed
WO-2019067587-A1 USE OF METFORMIN AND ANALOGS THEREOF TO REDUCE RAN PROTEIN LEVELS IN THE TREATMENT OF NEUROLOGICAL DISORDERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2019-04-04 — — WO disclosed