Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22458651 | 0.94 | YTHDC1 (0.51) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL25468357 | 0.78 | CCNB2 (0.41) | YTHDC1CDK1ADORA1CCNB2CCNB1 | |
| SCHEMBL21562162 | 0.76 | YTHDC1 (0.67) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL18520986 | 0.71 | YTHDC1 (0.63) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL13922352 | 0.71 | YTHDC1 (0.51) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL20857256 | 0.70 | YTHDC1 (0.67) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL16710431 | 0.69 | YTHDC1 (0.70) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL26562076 | 0.66 | YTHDC1 (0.65) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL24490547 | 0.66 | YTHDC1 (0.59) | YTHDC1CDK1ADORA1CYP1A2CYP3A4 | |
| SCHEMBL19661682 | 0.65 | CYP1A2 (0.49) | YTHDC1ADORA1CYP1A2CYP3A4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246480-B2 | Compounds for the treatment of cancer | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246480-B2 | Compounds for the treatment of cancer | TP53, MYC, CDC73 | YTHDC1 4534/4885CDK1 236/4885ADORA1 4601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.