Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472357 | 0.88 | IDO1 (0.46) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL18427934 | 0.88 | IDO1 (0.46) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16970719 | 0.87 | IDO1 (0.49) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16971143 | 0.85 | IDO1 (0.46) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16971233 | 0.81 | IDO1 (0.44) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16970747 | 0.80 | IDO1 (0.49) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16971148 | 0.79 | IDO1 (0.42) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16971091 | 0.77 | IDO1 (0.41) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16970749 | 0.77 | IDO1 (0.64) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL16970691 | 0.77 | IDO1 (0.64) | IDO1SMN1; SMN2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246406-B2 | Beta-substituted beta-amino acids and analogs as chemotherapeutic agents and uses thereof | QUADRIGA BIOSCIENCES, INC. (US) | 2019-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246406-B2 | Beta-substituted beta-amino acids and analogs as chemotherapeutic agents and uses thereof | SLC3A2, SLC7A1, SLC43A1 | IDO1 1294/4885SMN1; SMN2 3001/4885ALDH1A1 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.