SCHEMBL2085974

SCHEMBL2085974

CC[N+](C(C)C)(C(C)C)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145014 0.79 TSHR (0.33)
Formic Acid SCHEMBL19181191 0.65
SCHEMBL1132483 0.62 TSHR (0.31)
Hydrogen Sulfide SCHEMBL11755188 0.61
SCHEMBL1832260 0.60 SLC22A1 (0.41)
SCHEMBL7711081 0.60
Hydrochloric Acid SCHEMBL28018964 0.60 KDM4E (0.35)
SCHEMBL2766443 0.60 TSHR (0.41)
Water SCHEMBL10899203 0.58 TSHR (0.39)
Bromide SCHEMBL14890343 0.58 TSHR (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208641-B1 MULTI-SYNTHETIZER AND SEMI-AUTOMATIC SYNTHESIS PROCESS OF PEPTIDES IN THE SOLID PHASE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-09-20 EP claimed
US-20110052612-A1 SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2011-03-03 US disclosed
US-20090163517-A1 BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES BINGGELI ALFRED 2009-06-25 US disclosed
EP-1889622-A1 SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2008-02-20 EP disclosed
US-6005093-A CONMPOUNDS USED AS REPLACEMENTS FOR ONE OR MORE COMPLEMENTARY NUCLEOSIDE BASES IN PROBES; ENABLE PHOTOACTIVE CROSSLINKING OF NUCLEIC ACID STRANDS IN HYBRIDIZATION ASSAYS AND THERAPEUTIC APPLICATIONS NAXCOR (US) 1999-12-21 US disclosed
EP-0827501-A4 NON-NUCLEOSIDIC COUMARIN DERIVATIVES AS POLYNUCLEOTIDE-CROSS-LINKING AGENTS NAXCOR (US) 1998-06-10 EP disclosed
EP-0827501-A1 NON-NUCLEOSIDIC COUMARIN DERIVATIVES AS POLYNUCLEOTIDE-CROSS-LINKING AGENTS NAXCOR (US) 1998-03-11 EP disclosed
EP-0478775-B1 PEPTIDE DERIVATIVES MITSUBISHI CHEM CORP (JP) 1997-07-09 EP disclosed
US-4748002-A Semi-automatic, solid-phase peptide multi-synthesizer and process for the production of synthetic peptides by the use of the multi-synthesizer CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1988-05-31 US disclosed
US-4438029-A CONTROLLING SMOOTH MUSCLE CONTRACTION, HISTAMINE RELEASE, AND VASCULAR PERMEABILITY RESEARCH CORPORATION (US) 1984-03-20 US disclosed