Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.63 |
| ▸ | TAS1R2 | Q8TE23 | 11/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20662809 | 0.88 | TAS1R3 (0.78) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL701799 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1NPC1 | |
| SCHEMBL702935 | 0.68 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL702936 | 0.68 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL20662806 | 0.67 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL20861071 | 0.66 | TAS1R3 (0.79) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL20860881 | 0.65 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2HSD17B2 | |
| SCHEMBL8253156 | 0.65 | PDPK1 (0.55) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16421257 | 0.65 | PDPK1 (0.55) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL702097 | 0.64 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659881-B1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC (US) | 2019-04-03 | — | — | EP | disclosed |