Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21073942 | 1.00 | KMT2A (0.38) | KMT2APTGS1PTGS2NR3C1CASP1 | |
| SCHEMBL21073943 | 1.00 | KMT2A (0.38) | KMT2APTGS1PTGS2NR3C1CASP1 | |
| SCHEMBL23286124 | 0.96 | NR3C1 (0.38) | KMT2ANR3C1CASP1SMN1; SMN2HPGD | |
| SCHEMBL22459925 | 0.92 | HDAC3 (0.41) | KMT2APTGS1PTGS2NR3C1CASP1 | |
| SCHEMBL24835046 | 0.92 | HDAC3 (0.41) | KMT2APTGS1PTGS2NR3C1CASP1 | |
| SCHEMBL23071942 | 0.92 | NR3C1 (0.41) | KMT2ANR3C1CASP1SMN1; SMN2HPGD | |
| SCHEMBL17823174 | 0.92 | PTGS1 (0.40) | KMT2APTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL17823173 | 0.92 | PTGS1 (0.40) | KMT2APTGS1PTGS2SMN1; SMN2HPGD | |
| SCHEMBL22990414 | 0.91 | SMN1; SMN2 (0.38) | KMT2APTGS1PTGS2NR3C1CASP1 | |
| SCHEMBL25413283 | 0.91 | KMT2A (0.37) | KMT2APTGS1PTGS2NR3C1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019065964-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | 第一三共株式会社 | 2019-04-04 | — | — | WO | disclosed |