⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342654 | 0.79 | — | — | |
| SCHEMBL1843191 | 0.77 | — | — | |
| SCHEMBL5261460 | 0.77 | — | — | |
| SCHEMBL19385917 | 0.77 | — | — | |
| SCHEMBL26907369 | 0.77 | — | — | |
| SCHEMBL7966443 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6707941 | 0.76 | GABRA1 (0.39) | — | |
| SCHEMBL9965027 | 0.76 | MAPK1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL2010801 | 0.76 | GABRA1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL5114469 | 0.74 | GABRA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584755-B2 | Dihydrothieno[3,2-b]pyridine compounds | IDEAYA BIOSCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| WO-2019067442-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2019-04-04 | — | — | WO | disclosed |