Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 16/20 | 0.84 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.84 |
| ▸ | PRKCA | P17252 | 8/20 | 0.73 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 8/20 | 0.73 |
| ▸ | PRKCG | P05129 | 8/20 | 0.73 |
| ▸ | PRKCZ | Q05513 | 8/20 | 0.73 |
| ▸ | PRKCB | P05771 | 7/20 | 0.73 |
| ▸ | PRKCH | P24723 | 7/20 | 0.73 |
| ▸ | PRKCI | P41743 | 7/20 | 0.73 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.73 |
| ▸ | PRKD1 | Q15139 | 7/20 | 0.73 |
| ▸ | EGFR | P00533 | 6/20 | 0.69 |
| ▸ | PRKACA | P17612 | 6/20 | 0.69 |
| ▸ | PRKACG | P22612 | 5/20 | 0.69 |
| ▸ | PRKACB | P22694 | 5/20 | 0.69 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | KDR | P35968 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22765174 | 0.91 | PRKCQ (1.00) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL26076886 | 0.89 | PRKCQ (0.85) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL12570343 | 0.88 | PRKCQ (1.00) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL20841734 | 0.88 | PRKCQ (1.00) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL22765238 | 0.88 | PRKCQ (1.00) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL12570346 | 0.88 | PRKCQ (1.00) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL20865123 | 0.88 | PRKCQ (0.80) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL12963562 | 0.88 | PRKCQ (0.79) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL638600 | 0.85 | PRKCQ (0.83) | PRKCQROCK2PRKCAMAP3K5PRKD3 | |
| SCHEMBL22765429 | 0.85 | PRKCQ (0.83) | PRKCQROCK2PRKCAMAP3K5PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067396-A1 | ZAP-70 KINASE INHIBITOR COMPOSITIONS, METHODS AND USES THEREOF | SNAP BIO, INC. (US) | 2019-04-04 | — | — | WO | disclosed |