Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.48 |
| ▸ | CCKAR | P32238 | 10/20 | 0.48 |
| ▸ | NOTCH1 | P46531 | 4/20 | 0.39 |
| ▸ | NOTCH3 | Q9UM47 | 3/20 | 0.39 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24611978 | 0.86 | CCKBR (0.54) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL20866842 | 0.86 | CCKBR (0.54) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL24611916 | 0.86 | CCKBR (0.51) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL24612270 | 0.86 | CCKBR (0.51) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20867299 | 0.85 | CCKBR (0.52) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20866815 | 0.85 | CCKBR (0.49) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20867297 | 0.85 | CCKBR (0.49) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL24612150 | 0.83 | CCKBR (0.49) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL24611948 | 0.83 | CCKBR (0.56) | CCKBRCCKARNOTCH1NOTCH3RBPJ | |
| SCHEMBL20866843 | 0.83 | CCKBR (0.46) | CCKBRCCKARNOTCH1NOTCH3RBPJ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |