SCHEMBL20867009

SCHEMBL20867009

N=C(N[C@H]1N=C(c2ccccc2)c2ccccc2NC1=O)OC(=N)c1cccnc1N1CCOCC1

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 17/20 0.56
CCKAR P32238 4/20 0.48
CCKBR P32239 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20866611 1.00 CBLB (0.56) CBLBCCKARCCKBR
SCHEMBL20866655 0.92 CBLB (0.48) CBLBCCKARCCKBR
SCHEMBL20866962 0.92 CCKBR (0.49) CBLBCCKARCCKBR
SCHEMBL20866866 0.91 CCKAR (0.48) CBLBCCKARCCKBR
SCHEMBL20867028 0.91 CCKBR (0.48) CBLBCCKARCCKBR
SCHEMBL24612237 0.90 CBLB (0.48) CBLBCCKARCCKBR
SCHEMBL20867128 0.90 CBLB (0.48) CBLBCCKARCCKBR
SCHEMBL24612025 0.90 CBLB (0.53) CBLBCCKARCCKBR
SCHEMBL20866730 0.90 CBLB (0.57) CBLBCCKARCCKBR
SCHEMBL20866731 0.90 CBLB (0.57) CBLBCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019067864-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2019-04-04 WO disclosed