SCHEMBL20867232

SCHEMBL20867232

N#Cc1ccc(F)c(-c2cc(-c3nc(-c4ccccc4)cc(-c4ccccc4)n3)ccc2F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 3/20 0.48
HPGD P15428 4/20 0.45
KDM4E B2RXH2 4/20 0.45
ADORA2A P29274 3/20 0.45
ADORA1 P30542 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
RXFP1 Q9HBX9 1/20 0.45
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SQOR Q9Y6N5 1/20 0.43
MYC P01106 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
NTSR1 P30989 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
GABRG2 P18507 2/20 0.43
GABRB3 P28472 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20867408 0.96 ABCG2 (0.50) ABCG2HPGDKDM4EADORA2AADORA1
SCHEMBL20867334 0.93 ABCG2 (0.45) ABCG2HPGDKDM4EADORA2AADORA1
SCHEMBL20867241 0.93 ABCG2 (0.45) ABCG2HPGDKDM4EADORA2AADORA1
SCHEMBL20794068 0.92 ABCG2 (0.47) ABCG2KDM4EMAPK1MEN1KMT2A
SCHEMBL20867332 0.90 ABCG2 (0.47) ABCG2HPGDKDM4EADORA2AADORA1
SCHEMBL20867244 0.90 ABCG2 (0.47) ABCG2HPGDKDM4EADORA2AADORA1
SCHEMBL20843342 0.87 ABCG2 (0.48) ABCG2HPGDKDM4ENPSR1RXFP1
SCHEMBL20867230 0.86 ABCG2 (0.48) ABCG2HPGDKDM4EADORA2AADORA1
SCHEMBL20793912 0.85 ABCG2 (0.44) ABCG2KDM4EADORA2AADORA1MAPK1
SCHEMBL20848945 0.84 ACLY (0.53) CYP11B1CYP11B2GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019063288-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELCTRONIC DEVICES CYNORA GMBH (DE) 2019-04-04 WO disclosed