Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.51 |
| ▸ | CCKAR | P32238 | 9/20 | 0.51 |
| ▸ | CBLB | Q13191 | 5/20 | 0.42 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.41 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20867180 | 0.95 | CCKBR (0.50) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20867031 | 0.94 | CCKAR (0.50) | CCKBRCCKARCBLB | |
| SCHEMBL20867088 | 0.94 | CCKAR (0.50) | CCKBRCCKARCBLB | |
| SCHEMBL24612175 | 0.93 | CCKBR (0.48) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL20867175 | 0.93 | CCKBR (0.48) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL24612196 | 0.92 | CCKBR (0.50) | CCKBRCCKARCBLBNOTCH1RBPJ | |
| SCHEMBL20866768 | 0.92 | CCKBR (0.50) | CCKBRCCKARCBLBNOTCH1RBPJ | |
| SCHEMBL20866910 | 0.89 | CCKAR (0.49) | CCKBRCCKARCBLBNOTCH1RBPJ | |
| SCHEMBL20867029 | 0.89 | CCKAR (0.48) | CCKBRCCKARCBLBNOTCH1 | |
| SCHEMBL20867294 | 0.89 | CCKBR (0.49) | CCKBRCCKARCBLBNOTCH1RBPJ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |