Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20868353 | 0.89 | SCN9A (0.51) | SCN9ASCN7ASCN5A | |
| SCHEMBL20868523 | 0.88 | SCN9A (0.47) | SCN9AMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL20868203 | 0.87 | NPC1 (0.39) | NPC1SCN9AHSD11B1OPRL1MEN1 | |
| SCHEMBL20868344 | 0.87 | SCN7A (0.47) | SCN9ASCN7ASCN5A | |
| SCHEMBL20868025 | 0.79 | SCN9A (0.45) | SCN9ASCN7ASCN5A | |
| SCHEMBL20868012 | 0.77 | SCN9A (0.60) | SCN9ASCN7ASCN5A | |
| SCHEMBL20868267 | 0.77 | SCN9A (0.51) | SCN9ASCN7ASCN5A | |
| SCHEMBL20868201 | 0.77 | SCN5A (0.48) | SCN9ASCN7ASCN5A | |
| SCHEMBL20868072 | 0.76 | SCN5A (0.45) | SCN9ASCN7ASCN5A | |
| SCHEMBL20868381 | 0.75 | SCN9A (0.54) | SCN9ASCN7ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019062848-A1 | N-(SUBSTITUTED SULFONYL)BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2019-04-04 | — | — | WO | disclosed |