Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 19/20 | 0.53 |
| ▸ | LGALS9 | O00182 | 10/20 | 0.53 |
| ▸ | LGALS7; LGALS7B | P47929 | 9/20 | 0.53 |
| ▸ | LGALS8 | O00214 | 7/20 | 0.53 |
| ▸ | LGALS1 | P09382 | 4/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869036 | 0.99 | LGALS3 (0.52) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL20868575 | 0.98 | LGALS3 (0.53) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL23374297 | 0.87 | LGALS3 (0.57) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL23374275 | 0.86 | LGALS3 (0.58) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL23374446 | 0.78 | LGALS3 (0.54) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL19580099 | 0.72 | LGALS3 (0.73) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL13385541 | 0.70 | LGALS3 (0.74) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL10067559 | 0.70 | LGALS3 (0.74) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL3277373 | 0.70 | LGALS3 (1.00) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 | |
| SCHEMBL1425152 | 0.70 | LGALS3 (1.00) | LGALS3LGALS9LGALS7; LGALS7BLGALS8LGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067702-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-04 | — | — | WO | disclosed |