⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49955 | 0.91 | — | — | |
| Nitrogen SCHEMBL27656846 | 0.87 | — | — | |
| SCHEMBL27839446 | 0.83 | — | — | |
| SCHEMBL27816261 | 0.83 | — | — | |
| SCHEMBL27735222 | 0.83 | — | — | |
| Methane SCHEMBL28861313 | 0.83 | — | — | |
| SCHEMBL2235964 | 0.83 | ALDH1A1 (0.33) | — | |
| SCHEMBL27750254 | 0.83 | — | — | |
| SCHEMBL1549115 | 0.83 | — | — | |
| SCHEMBL182511 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383005-A | The preparation method of the acetic acid of 6 methyl 2 (4 aminomethyl phenyl) imidazo [1,2 a] pyridine 3 | 华东理工大学 | 2017-11-24 | — | — | CN | claimed |
| CN-108473483-A | Compound for medical applications | 澳大利亚生物医学公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-107383005-A | The preparation method of the acetic acid of 6 methyl 2 (4 aminomethyl phenyl) imidazo [1,2 a] pyridine 3 | 华东理工大学 | 2017-11-24 | — | — | CN | disclosed |
| US-9133073-B2 | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| US-8604083-B2 | Method for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130281705-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORP (US) | 2013-10-24 | — | — | US | disclosed |
| EP-1461323-B1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORP (US) | 2013-10-09 | — | — | EP | disclosed |
| US-8552062-B2 | Methods for the treatment of metabolic disorders such as diabetes | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-10-08 | — | — | US | disclosed |
| US-8487000-B2 | 4-(3-(2,6-Dimethoxybenzyloxy)phenyl)-4-oxobutyric acid or derivatives for treatment of insulin resistance syndrome, diabetes, cachexia, hyperlipidemia, fatty liver disease, obesity, atherosclerosis or arteriosclerosis | Wellstat Therapertics Corporation (US) | 2013-07-16 | — | — | US | disclosed |
| CN-101128469-B | Protease inhibitor precursor synthesis | TIBOTEC PHARM LTD | 2012-11-14 | — | — | CN | disclosed |
| EP-1224168-A1 | ANTIFUNGAL ENEDIYNES | PHYTERA, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
| CN-1347420-A | Growth-promoting hormone secretagogues | LILLY CO ELI (US) | 2002-05-01 | — | — | CN | disclosed |
| EP-1060172-A4 | SYNTHESIS OF PACLITAXEL BACCATIN III BY PROTECTING THE 7-HYDROXYL USING A STRONG BASE AND AN ELECTROPHILE | BRISTOL MYERS SQUIBB CO (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6307071-B1 | Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile | BRISTOL-MYERS SQUIBB COMPANY | 2001-10-23 | — | — | US | disclosed |
| CN-1305473-A | N,N-disubstituded amide for inhibit binding of integrins to their receptors protein | TEXAS BIOTECHNOLOGY CORP (US) | 2001-07-25 | — | — | CN | disclosed |
| US-6242583-B1 | COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | disclosed |
| WO-2001025197-A1 | ANTIFUNGAL ENEDIYNES | PHYTERA, INC. (US) | 2001-04-12 | — | — | WO | disclosed |
| EP-1060172-A1 | SYNTHESIS OF PACLITAXEL BACCATIN III BY PROTECTING THE 7-HYDROXYL USING A STRONG BASE AND AN ELECTROPHILE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-12-20 | — | — | EP | disclosed |
| US-6020507-A | Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| WO-1999045001-A1 | SYNTHESIS OF PACLITAXEL BACCATIN III BY PROTECTING THE 7-HYDROXYL USING A STRONG BASE AND AN ELECTROPHILE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-10 | — | — | WO | disclosed |