Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855365 | 0.86 | ALDH1A1 (0.33) | MAPTTP53ALDH1A1PTGS1PTGS2 | |
| SCHEMBL20870977 | 0.84 | MAPT (0.36) | MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL20871062 | 0.84 | MAPT (0.31) | MAPT | |
| SCHEMBL20871063 | 0.77 | MAPT (0.37) | MAPTLMNATP53THRBPTGS1 | |
| SCHEMBL20870958 | 0.77 | PTGS1 (0.38) | PTGS1PTGS2 | |
| SCHEMBL20871122 | 0.75 | — | — | |
| SCHEMBL20870740 | 0.75 | CHRNA7 (0.31) | — | |
| SCHEMBL20871628 | 0.73 | — | — | |
| SCHEMBL20871591 | 0.70 | — | — | |
| SCHEMBL20870953 | 0.69 | DAO (0.33) | MAPTLMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019062802-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USES IN AGRICULTURE RELATED APPLICATION | DONGGUAN HEC TECH R & D CO., LTD. (CN) | 2019-04-04 | — | — | WO | disclosed |