Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19023830 | 1.00 | FUCA1 (0.46) | FUCA1RECQLSMN1; SMN2S1PR1S1PR5 | |
| SCHEMBL19023831 | 1.00 | FUCA1 (0.46) | FUCA1RECQLSMN1; SMN2S1PR1S1PR5 | |
| SCHEMBL12723223 | 0.85 | FUCA1 (0.53) | FUCA1S1PR1S1PR5SIGMAR1ACHE | |
| SCHEMBL25933663 | 0.85 | FUCA1 (0.53) | FUCA1S1PR1S1PR5SIGMAR1ACHE | |
| SCHEMBL3226519 | 0.85 | RECQL (0.49) | FUCA1RECQLSMN1; SMN2MEN1CYP2D6 | |
| SCHEMBL3917960 | 0.81 | FUCA1 (0.43) | FUCA1RECQLSMN1; SMN2S1PR1S1PR5 | |
| SCHEMBL4889413 | 0.81 | FUCA1 (0.43) | FUCA1RECQLSMN1; SMN2S1PR1S1PR5 | |
| SCHEMBL19024339 | 0.81 | FUCA1 (0.43) | FUCA1RECQLSMN1; SMN2S1PR1S1PR5 | |
| SCHEMBL17220043 | 0.81 | FUCA1 (0.43) | FUCA1RECQLSMN1; SMN2S1PR1S1PR5 | |
| SCHEMBL3917962 | 0.81 | FUCA1 (0.43) | FUCA1RECQLSMN1; SMN2S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190106412-A1 | SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANES AS KETOHEXOKINASE INHIBITORS | PFIZER INC. (US) | 2019-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106412-A1 | SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANES AS KETOHEXOKINASE INHIBITORS | HK1, GCK, KHK | FUCA1 1552/4885RECQL 4745/4885SMN1; SMN2 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.