SCHEMBL3226519

SCHEMBL3226519

CS(=O)(=O)CC1C2CCC1CN(Cc1ccccc1)C2

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 1/20 0.45
DRD2 P14416 2/20 0.45
DRD3 P35462 1/20 0.45
MEN1 O00255 1/20 0.45
CYP2D6 P10635 1/20 0.45
KMT2A Q03164 1/20 0.45
HTR2A P28223 1/20 0.44
FUCA1 P04066 2/20 0.44
ACHE P22303 1/20 0.44
GRIN2B Q13224 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19023831 0.85 FUCA1 (0.46) RECQLSMN1; SMN2ALDH1A1DRD2MEN1
SCHEMBL19023830 0.85 FUCA1 (0.46) RECQLSMN1; SMN2ALDH1A1DRD2MEN1
SCHEMBL20875293 0.85 FUCA1 (0.46) RECQLSMN1; SMN2ALDH1A1DRD2MEN1
SCHEMBL4181243 0.82 RECQL (0.46) RECQLSMN1; SMN2ALDH1A1DRD2MEN1
SCHEMBL11413096 0.79 FUCA1 (0.60) ALDH1A1DRD2DRD3CYP2D6FUCA1
SCHEMBL4193483 0.78 RECQL (0.48) RECQLSMN1; SMN2ALDH1A1DRD2MEN1
SCHEMBL26709646 0.78 RECQL (0.48) RECQLSMN1; SMN2ALDH1A1DRD2MEN1
SCHEMBL16837173 0.77 FUCA1 (0.58) DRD2DRD3CYP2D6FUCA1ACHE
SCHEMBL4191012 0.76 FUCA1 (0.50) ALDH1A1DRD2DRD3CYP2D6FUCA1
SCHEMBL4198217 0.76 FUCA1 (0.54) ALDH1A1DRD2DRD3FUCA1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056496-A1 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056496-A1 MUSCARINIC RECEPTOR ANTAGONISTS CHRM3, CHRM5, CHRM2 RECQL 1918/4885SMN1; SMN2 2082/4885ALDH1A1 2093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.