SCHEMBL20875707

SCHEMBL20875707

ClCP(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ESR1 P03372 4/20 0.35
ESR2 Q92731 4/20 0.35
ALDH1A1 P00352 3/20 0.33
TRPA1 O75762 1/20 0.33
MAPK1 P28482 1/20 0.33
GSK3B P49841 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.33
CALM1 P0DP23 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
CYP19A1 P11511 1/20 0.31
RECQL P46063 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2227011 0.78 CYP3A4 (0.41) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL10595565 0.77 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL9806656 0.77 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL114543 0.75 CYP3A4 (0.50) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL27343 0.75 CYP3A4 (0.50) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL2273884 0.74 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL9806634 0.74 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL29442088 0.74 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL5079169 0.74 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL9806642 0.74 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120169326-B Silicon-based adsorbent for oil gas recovery and preparation method thereof 上海聚宸新能源科技有限公司 2025-07-18 CN disclosed
CN-120169326-A Silicon-based adsorbent for oil gas recovery and preparation method thereof 上海聚宸新能源科技有限公司 2025-06-20 CN disclosed
CN-119462753-A Imidazole-phosphine bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphine bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2025-02-18 CN disclosed
CN-119462753-A Imidazole-phosphine bidentate ligand, synthesis method thereof, metal catalyst prepared from imidazole-phosphine bidentate ligand and application of metal catalyst 中国石油化工股份有限公司 2025-02-18 CN disclosed
CN-117463405-A Ferroferric oxide loaded bidentate chelating platinum catalyst and preparation method and application thereof 江西省科学院应用化学研究所 2024-01-30 CN disclosed
CN-117417533-A Preparation method of organosilicon polymer 江西省科学院应用化学研究所 2024-01-19 CN disclosed
US-11377398-B2 Ethylene selective oligomerization catalyst systems and method for ethylene oligomerization using the same UNIV TIANJIN SCIENCE & TECH (CN) 2022-07-05 US disclosed
CN-109476680-B Organic magnesium phosphide, process for producing the same, complex thereof, process for producing the same, and process for producing organic phosphorus compound using the same 北兴化学工业株式会社 2022-06-28 CN disclosed
CN-108031493-B Catalyst system for selective oligomerization of ethylene and ethylene oligomerization reaction method 天津科技大学 2020-11-06 CN disclosed
US-20190106366-A1 Ethylene selective oligomerization catalyst systems and method for ethylene oligomerization using the same TIANJIN UNIV OF SCIENCE&TECHNOLOGY (CN) 2019-04-11 US disclosed
CN-108031493-A Catalyst system and ethylene oligomerization reaction method for ethylene selectivity oligomerisation 天津科技大学 2018-05-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377398-B2 Ethylene selective oligomerization catalyst systems and method for ethylene oligomerization using the same F8, EXOC4, NOD1 CYP3A4 317/4885TDP1 3132/4885ESR1 4/4885
US-20190106366-A1 Ethylene selective oligomerization catalyst systems and method for ethylene oligomerization using the same F8, EXOC4, ETV6 CYP3A4 375/4885TDP1 3456/4885ESR1 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.