Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 4/20 | 0.62 |
| ▸ | CPA3 | P15088 | 2/20 | 0.62 |
| ▸ | CPB1 | P15086 | 1/20 | 0.62 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388453 | 0.89 | AKR1B1 (0.57) | CPA1CPA3CPB1CPB2AKR1B1 | |
| SCHEMBL16491918 | 0.84 | AKR1B1 (0.52) | CPA1CPA3CPB1CPB2AKR1B1 | |
| SCHEMBL13857860 | 0.82 | PPARG (0.50) | AKR1B1CYP1A2 | |
| SCHEMBL16151060 | 0.82 | AKR1B1 (0.50) | CPA1CPA3CPB1CPB2AKR1B1 | |
| SCHEMBL7299030 | 0.81 | CPA1 (0.61) | CPA1CPA3CPB1CPB2FOLH1 | |
| SCHEMBL13990183 | 0.81 | CPA1 (0.61) | CPA1CPA3CPB1CPB2FOLH1 | |
| SCHEMBL17537592 | 0.80 | CPA1 (0.65) | CPA1CPA3CPB1CPB2FOLH1 | |
| SCHEMBL490938 | 0.79 | KMT2A (0.60) | AKR1B1CYP1A2TSHRHSPA5 | |
| SCHEMBL5079144 | 0.79 | AKR1B1 (0.55) | CPA1CPA3CPB1CPB2AKR1B1 | |
| SCHEMBL9863542 | 0.79 | AKR1B1 (0.55) | CPA1CPA3CPB1CPB2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691624-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. | Sorbonne Université (FR) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019068788-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. | Sorbonne Université (FR) | 2019-04-11 | — | — | WO | disclosed |