Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL301655 | 1.00 | PDE4A (0.58) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Citric Acid SCHEMBL301849 | 0.98 | PDE4A (0.56) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Gluconic Acid SCHEMBL27097002 | 0.98 | PDE4A (0.56) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Gluconic Acid SCHEMBL28829555 | 0.97 | PDE4A (0.54) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Citric Acid SCHEMBL2518499 | 0.94 | PDE4A (0.51) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Gluconic Acid SCHEMBL28106011 | 0.94 | PDE4A (0.66) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Citric Acid SCHEMBL3021271 | 0.94 | PDE4A (0.66) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Citric Acid SCHEMBL9052947 | 0.92 | PDE4A (0.63) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Citric Acid SCHEMBL10438268 | 0.92 | PDE4A (0.63) | PDE4AALDH1A1LMNAUSP2SLCO1B1 | |
| Citric Acid SCHEMBL301965 | 0.92 | PDE4A (0.63) | PDE4AALDH1A1LMNAUSP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691625-A1 | GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF MICROBIAL INFECTIONS | Gedea Biotech AB (SE) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019068862-A1 | GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF MICROBIAL INFECTIONS | GEDEA BIOTECH AB (SE) | 2019-04-11 | — | — | WO | disclosed |