Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17788910 | 0.94 | ELANE (0.56) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL56436 | 0.91 | ELANE (0.69) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL10024013 | 0.89 | ELANE (0.50) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL450454 | 0.88 | ELANE (0.61) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL13133147 | 0.86 | ELANE (0.69) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL17433304 | 0.85 | ELANE (0.62) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL803168 | 0.85 | ELANE (0.62) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL14173256 | 0.85 | ELANE (0.62) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL16334971 | 0.85 | ELANE (0.68) | ELANEKMT2AATMMAPTLMNA | |
| SCHEMBL14173258 | 0.85 | ELANE (0.62) | ELANEKMT2AATMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251841-B2 | Polymeric depots for localization of agent to biological sites | TRUSTEES OF BOSTON UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10251841-B2 | Polymeric depots for localization of agent to biological sites | CD68, LPXN, CXCL12 | ELANE 131/4885KMT2A 4643/4885ATM 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.