SCHEMBL450454

SCHEMBL450454

C=C(C)C(=O)Oc1ccc(OC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.61
MAPT P10636 1/20 0.60
KMT2A Q03164 2/20 0.56
ATM Q13315 1/20 0.56
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
CA1 P00915 5/20 0.47
CA2 P00918 5/20 0.47
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
PARP1 P09874 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP2 Q9UGN5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18104469 0.94 ELANE (0.56) ELANEMAPTKMT2AATMCES2
SCHEMBL19881850 0.94 ELANE (0.56) ELANEMAPTKMT2AATMCES2
SCHEMBL4946215 0.94 ELANE (0.56) ELANEMAPTKMT2AATMCES2
SCHEMBL56436 0.91 ELANE (0.69) ELANEMAPTKMT2AATMSMN1; SMN2
SCHEMBL2404682 0.91 ELANE (0.76) ELANEMAPTKMT2AATMCES2
SCHEMBL18061416 0.89 ELANE (0.51) ELANEMAPTKMT2AATMCES2
SCHEMBL11558754 0.89 MAPT (0.57) ELANEMAPTKMT2AATMSMN1; SMN2
SCHEMBL12234115 0.89 ELANE (0.51) ELANEMAPTKMT2AATMCES2
SCHEMBL687176 0.89 ELANE (0.51) ELANEMAPTKMT2AATMCES2
SCHEMBL10015754 0.89 ELANE (0.59) ELANEMAPTKMT2AATMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795787-B Color electrophoretic display 伊英克公司 2024-10-18 CN claimed
CN-114585656-B Method and system for preparing high molecular weight ethylene-based polymers 埃克森美孚化学专利公司 2024-03-05 CN claimed
US-20220413323-A1 COMPOSITE ELECTROPHORETIC PARTICLES HAVING POLYMER SHELLS INCLUDING FIRST AND SECOND MONOMERIC UNITS E INK CORPORATION 2022-12-29 US claimed
CN-115322100-A Delta, epsilon-alkenyl ketone compound and preparation method and application thereof 南京工业大学 2022-11-11 CN claimed
US-11460722-B2 Colored electrophoretic displays E INK CORPORATION (US) 2022-10-04 US claimed
CN-114585656-A Process and system for preparing high molecular weight ethylene-based polymers 埃克森美孚化学专利公司 2022-06-03 CN claimed
EP-3966630-A1 COLORED ELECTROPHORETIC DISPLAYS E Ink Corporation (US) 2022-03-16 EP claimed
CN-113795787-A Color electrophoretic display 伊英克公司 2021-12-14 CN claimed
CN-113200856-A Trifluoromethyl propylene compound and preparation method and application thereof 南京工业大学 2021-08-03 CN claimed
WO-2020231733-A1 COLORED ELECTROPHORETIC DISPLAYS E INK CORPORATION (US) 2020-11-19 WO claimed
US-20050220840-A1 Coating compositions for bioactive agents Surmodics Coatings, LLC 2005-10-06 US claimed
US-20050220841-A1 Coating compositions for bioactive agents Surmodics Coatings, LLC 2005-10-06 US claimed
US-20050220839-A1 Coating compositions for bioactive agents Surmodics Coatings, LLC 2005-10-06 US claimed
US-20050220843-A1 Coating compositions for bioactive agents Surmodics Coatings, LLC 2005-10-06 US claimed
US-20030225230-A1 Polymers for antifouling coatings and a process for the preparation thereof JOTUN A/S 2003-12-04 US claimed
EP-0841380-B1 Method of making polymeric binders and use thereof in antifouling paints WITCO GMBH (DE) 1999-08-25 EP claimed
US-5891935-A Process for preparing polymeric binders and their use for antifouling paint systems WITCO GMBH (DE) 1999-04-06 US claimed
EP-0833870-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-04-08 EP claimed
WO-1996041842-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO claimed
US-5374487-A Compatible polymeric mixtures ROHM GMBH (DE) 1994-12-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050220839-A1 Coating compositions for bioactive agents BMP2, FGF23, TGFB1 ELANE 257/4885MAPT 3986/4885KMT2A 4075/4885
US-20050220841-A1 Coating compositions for bioactive agents BMP2, FGF23, TGFB1 ELANE 257/4885MAPT 3986/4885KMT2A 4075/4885
US-20050220843-A1 Coating compositions for bioactive agents BMP2, FGF23, TGFB1 ELANE 257/4885MAPT 3986/4885KMT2A 4075/4885
US-20050220840-A1 Coating compositions for bioactive agents BMP2, FGF23, TGFB1 ELANE 257/4885MAPT 3986/4885KMT2A 4075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.