⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22646503 | 0.89 | RIPK1 (0.31) | — | |
| SCHEMBL20762554 | 0.86 | RIPK1 (0.31) | — | |
| SCHEMBL20078700 | 0.82 | RIPK1 (0.32) | — | |
| SCHEMBL21120509 | 0.80 | RIPK1 (0.32) | — | |
| SCHEMBL24119267 | 0.80 | RIPK1 (0.32) | — | |
| SCHEMBL25511390 | 0.80 | RIPK1 (0.33) | — | |
| SCHEMBL20762604 | 0.79 | RIPK1 (0.31) | — | |
| SCHEMBL22646487 | 0.77 | RIPK1 (0.32) | — | |
| SCHEMBL24942295 | 0.72 | RIPK1 (0.34) | — | |
| SCHEMBL22096273 | 0.72 | CA12 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251898-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |