⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757147 | 0.97 | — | — | |
| Dimethylamine SCHEMBL28743113 | 0.94 | CA2 (0.40) | — | |
| SCHEMBL27253156 | 0.76 | CA2 (0.47) | — | |
| SCHEMBL2751819 | 0.76 | — | — | |
| SCHEMBL3310419 | 0.76 | CA2 (0.41) | — | |
| SCHEMBL23667669 | 0.75 | — | — | |
| SCHEMBL10025586 | 0.75 | — | — | |
| SCHEMBL27476462 | 0.75 | CA2 (0.40) | — | |
| SCHEMBL13756044 | 0.75 | — | — | |
| SCHEMBL177789 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4331607-A2 | PHARMACEUTICAL COMPOSITION CONTAINING 2-{4-[N-(5,6-DIPHENYLPYRAZIN-2-YL)-N-ISOPROPYLAMINO]BUTYLOXY}-N-(METHYLSULFONYL)ACETAMIDE | Nippon Shinyaku Co., Ltd. (JP) | 2024-03-06 | — | — | EP | claimed |
| EP-3596051-B1 | FUSED BICYCLIC COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | IMPETIS BIOSCIENCES LTD (IN) | 2022-04-27 | — | — | EP | claimed |
| WO-2017029594-A1 | PROCESSES FOR PREPARATION OF SELEXIPAG AND ITS AMORPHOUS FORM | DR. REDDY'S LABORATORIES LIMITED (IN) | 2017-02-23 | — | — | WO | claimed |
| EP-1590314-B1 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPÉ FARMACEUTICI S P A (IT) | 2015-08-05 | — | — | EP | claimed |
| CN-102099026-B | Therapeutic compositions containing macitentan | ACTELION PHARMACEUTICALS LTD | 2012-08-29 | — | — | CN | claimed |
| CN-102459198-A | Crystal | NIPPON SHINYAKU CO LTD | 2012-05-16 | — | — | CN | claimed |
| CN-102065864-A | Therapeutic agent for inflammatory bowel disease | NIPPON SHINYAKU CO LTD | 2011-05-18 | — | — | CN | claimed |
| CN-102065863-A | Therapeutic agent for spinal canal stenosis | NIPPON SHINYAKU CO LTD | 2011-05-18 | — | — | CN | claimed |
| US-7939548-B2 | Aminopyridines, e.g.,N-{[6-(aminomethyl)(2-pyridyl)]methyl}(2-{[2-(3-fluorophenyl)ethyl]amino}-5-(3-pyridyl)(3-pyridyl))carboxamide; smooth muscle myosin or non-muscle myosin modulator; hypotensive agent; asthma, COPD, bronchoconstrictive disease, glaucoma, pre-menstrual cramps, erectile dysfunction | CYTOKINETICS, INC. (US) | 2011-05-10 | — | — | US | claimed |
| US-7932270-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2011-04-26 | — | — | US | claimed |
| WO-1999052906-A1 | SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | claimed |
| WO-1999037153-A1 | SELECTIVE HERBICIDES BASED ON N-ARYL- TRIAZOLINE(THI)ONS AND N-ARLYSULFONYLAMINO (THIO)CARBONYL- TRIAZOLINE(THI) ONS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | claimed |
| WO-1999012913-A1 | SUBSTITUTED PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | claimed |
| US-5773420-A | Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-30 | — | — | US | claimed |
| EP-0480659-B1 | Use of Angiotensin-II antagonists for the manufacture of a medicament for the treatment of hyperuricemia | MERCK & CO INC (US) | 1996-09-04 | — | — | EP | claimed |
| US-5457022-A | Support having silver halide emulsion layer containing atleast one metallocene compound; fog-free and storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-10 | — | — | US | claimed |
| US-5336594-A | With spectrally sensitizing dye; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-09 | — | — | US | claimed |
| US-4891305-A | LASERS | RICOH CO., LTD. (JP) | 1990-01-02 | — | — | US | claimed |
| US-4656210-A | Stabilized polyvinyl chloride molding compositions | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1987-04-07 | — | — | US | claimed |
| EP-0049968-A1 | Pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1982-04-21 | — | — | EP | claimed |