Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27955102 | 0.91 | CTSL (0.48) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL4958137 | 0.89 | CTSL (0.49) | CTSLS1PR3CTSKCTSS | |
| SCHEMBL21848092 | 0.89 | CTSL (0.47) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL15782201 | 0.89 | CTSL (0.47) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL16690741 | 0.88 | CTSL (0.50) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL29840672 | 0.88 | CTSL (0.50) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL5575604 | 0.88 | CTSL (0.50) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL4597970 | 0.88 | CTSL (0.50) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL29127501 | 0.87 | CTSL (0.45) | CTSLS1PR3CTSKCTSSALDH1A1 | |
| SCHEMBL17691230 | 0.86 | CTSL (0.48) | CTSLS1PR3CTSKCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070087-B1 | INTERMEDIATES FOR THE SYNTHESIS OF CYCLIC P1 LINKERS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-04-10 | — | — | EP | disclosed |