Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.87 |
| ▸ | KLKB1 | P03952 | 11/20 | 0.73 |
| ▸ | F9 | P00740 | 8/20 | 0.73 |
| ▸ | F12 | P00748 | 1/20 | 0.68 |
| ▸ | PLAT | P00750 | 1/20 | 0.68 |
| ▸ | PROC | P04070 | 1/20 | 0.68 |
| ▸ | F7 | P08709 | 1/20 | 0.68 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.68 |
| ▸ | CTRL | P40313 | 1/20 | 0.68 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.68 |
| ▸ | CTRC | Q99895 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14700936 | 0.93 | F11 (1.00) | F11KLKB1F9F12PLAT | |
| SCHEMBL16526139 | 0.92 | F11 (0.86) | F11KLKB1F9F12PLAT | |
| SCHEMBL14700707 | 0.92 | F11 (0.86) | F11KLKB1F9F12PLAT | |
| SCHEMBL20879159 | 0.88 | F11 (1.00) | F11KLKB1F9F12PLAT | |
| SCHEMBL14700916 | 0.88 | F11 (1.00) | F11KLKB1F9F12PLAT | |
| SCHEMBL14700910 | 0.86 | F11 (1.00) | F11KLKB1F9F12PLAT | |
| SCHEMBL15594046 | 0.84 | KLKB1 (1.00) | F11KLKB1F9F12PLAT | |
| SCHEMBL18536142 | 0.84 | KLKB1 (1.00) | F11KLKB1F9F12PLAT | |
| SCHEMBL20879265 | 0.84 | F11 (1.00) | F11KLKB1F9F12PLAT | |
| SCHEMBL14700731 | 0.84 | F11 (1.00) | F11KLKB1F9F12PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070087-B1 | INTERMEDIATES FOR THE SYNTHESIS OF CYCLIC P1 LINKERS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-04-10 | — | — | EP | disclosed |